New device weighs at the attogram scale


January 20, 2014

Nano weight scale

MIT engineers have devised a way to measure the mass of particles with a resolution better than an attogram — one millionth of a trillionth of a gram. Weighing these tiny particles, including both synthetic nanoparticles and biological components of cells, could help researchers better understand their composition and function. “Now we can weigh small viruses, extracellular vesicles, and most of the engineered nanoparticles that are being used for nanomedicine,” says Selim Olcum, a postdoc in Manalis’ lab and one of the lead authors of a paper describing the system in this week’s issue of the Proceedings of the National Academy of Sciences. Graduate student Nathan Cermak is also a lead author of the paper, and Manalis, a member of MIT’s Koch Institute for Integrative Cancer Research, is the paper’s senior author. Researchers from the labs of MIT professors and Koch Institute members Angela Belcher and Sangeeta Bhatia also contributed to the study. Continue reading this article at MIT News.

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